01 - Preheat oven to 400°F. Line a baking sheet with parchment paper or lightly grease with cooking spray.
02 - Combine smoked paprika, garlic powder, onion powder, dried thyme, dried oregano, cayenne pepper, salt, and black pepper in a small bowl. Mix thoroughly to incorporate all spices evenly.
03 - Pat salmon fillets completely dry with paper towels. Brush both sides lightly with olive oil. Press Cajun spice mixture firmly onto the top and sides of each fillet, ensuring even coverage.
04 - Place seasoned salmon fillets on the prepared baking sheet, skin-side down if applicable. Space fillets evenly to allow proper heat circulation.
05 - Whisk together honey, fresh lemon juice, and melted unsalted butter in a separate small bowl until smooth and fully incorporated.
06 - Spoon half of the honey mixture evenly over the top of each salmon fillet, ensuring the spiced surface is lightly coated.
07 - Bake for 10 to 12 minutes, or until salmon reaches desired doneness and flakes easily when tested with a fork. The internal temperature should reach 145°F for fully cooked fish.
08 - Remove from oven and brush salmon with remaining honey glaze. Switch oven to broil and return salmon for 1 to 2 minutes until glaze bubbles and caramelizes lightly. Watch closely to prevent burning.
09 - Transfer salmon to serving plates. Sprinkle generously with fresh chopped parsley and accompany with lemon wedges for squeezing over the finished dish.